Figure 3. Hijacking of Host Translation Resources by Virus.
(A) The estimated distributions between active (equipped with the required accessory factors) and inactive (not equipped) ribosomes, and between ribosomes available for viral and host mRNAs are shown.
“- Time window -” indicates the time period during which viral translation is actively supported by host ribosomes.
(B) The estimated numbers of ribosomes available for viral translation and actually occupied by viral mRNAs are shown for the cases of infected BHK and DBT cells. Non-occupied ribosomes are considered as free ribosomes. When two lines coincide, no free ribosomes exist (all the available ribosomes are occupied by viral mRNAs). Vex(0) = 3.