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. Author manuscript; available in PMC: 2006 Sep 1.
Published in final edited form as: J Cell Biochem. 2006 Sep 1;99(1):52–70. doi: 10.1002/jcb.20989

Figure 1.

Figure 1

Scheme of protein misfolding and aggregation. In the scheme normally folded protein can undergo conformational transitions into various misfolded states that may aggregate in different morphologies. AFM images of Aβ peptide aggregated into protofilaments, toroids (rings) and fibrils are shown in plates (A), (B) and (C) respectively.