Table 2.
M. tuberculosis genes repressed two-fold or greater by INH treatment.
| ORF | Gene | Gene product | Fold change | Change p-value |
|---|---|---|---|---|
| Rv0263c | Conserved hypothetical protein | 3.2 | 0.000409 | |
| Rv0320 | Possible conserved exported protein | 5.7 | 0.000122 | |
| Rv0516c | Conserved hypothetical protein | 52 | 0.000000 | |
| Rv0950c | Conserved hypothetical protein | 4 | 0.000002 | |
| Rv1009 | rpfB | Probable resuscitation-promoting factor | 2.3 | 0.000004 |
| Rv1010 | ksgA | Probable dimethyladenosine transferase | 2.1 | 0.000000 |
| Rv1251c | Conserved hypothetical protein | 2.3 | 0.000000 | |
| Rv1365c | rsfA | Anti-anti-sigma factor | 5.7 | 0.001423 |
| Rv1555 | frdD | Probable fumarate reductase | 3.5 | 0.002189 |
| Rv1815 | Conserved hypothetical protein | 2.5 | 0.000005 | |
| Rv1885c | Conserved hypothetical protein | 5.3 | 0.000004 | |
| Rv1886c | fbpB | Secreted antigen 85-B | 5.3 | 0.000000 |
| Rv1892 | Probable membrane protein | 2.1 | 0.002189 | |
| Rv2190c | Conserved hypothetical protein | 4.9 | 0.000000 | |
| Rv2482c | plsB2 | Probable glycerol-3-phosphate acyltransferase | 2 | 0.000002 |
| Rv2626c | Conserved hypothetical protein | 2.1 | 0.000002 | |
| Rv2943 | Probable transposase for insertion sequence element is1533 | 2.1 | 0.000000 | |
| Rv3166c | Conserved hypothetical protein | 8.6 | 0.000996 | |
| Rv3263 | Probable DNA methylase | 2.3 | 0.001927 | |
| Rv3362c | Probable ATP/GTP-binding protein | 2.3 | 0.000122 | |
| Rv3603c | Conserved hypothetical alanine and leucine rich protein | 3.5 | 0.000429 |