Physiologic measurements in adult βENaC m/m
(black bars) and +/+ (white bars) mice on low-salt diets (0.1 g/kg
Na+; A–D). (A) Plasma
K+. For each group, n = 7. ∗∗,
P < 0.01. (B) Relative values of
urinary Na+ and K+ normalized with creatinine
(Creat). For βENaC +/+, n = 7; for βENaC
m/m, n = 6. (C) Plasma aldosterone
levels (nM). For each group, n = 6. ∗∗,
P < 0.01. (D) In vivo
measurements of ΔPDamil. For βENaC +/+,
n = 6; for βENaC m/m, n =
7. ∗∗, P < 0.01. (E) Mean
blood-pressure measurements in βENaC +/+ (n =
7) and m/m (n = 8) mice on normal-salt diets (NS;
3 g/kg Na+) and low-salt diets (LS; 0.1 g/kg
Na+). ∗, P < 0.05.