Table 1.

Studies using array-CGH on breast cancer samples or breast cancer cell lines

Patient source or cell line	Array platform	Resolution (Mb)	Ref.
2 Human cell lines, inclusing breast (BT474)	18,664 oligo nucleotides	~0.15	[16]
BC (n = 5)	32 k tiling BAC	Sub-Mb	[17]
Primary BC (n = 33), BC cell line (n = 27)	Genome-wide BAC and high resolution on 8p11-12	~1.5	[18]
FFPE BC (n = 44)	4153 BAC	<1	[24]
Comparison of FFPE with frozen BC	2464 BAC	1.5	[27]
Gain in 47% BC (unpublished results)	See Pinkel and coworkers [2]		[32]
FFPE BC (n = 31)	471 BAC/PAC	15	[47]
BRCA1 (n = 14), BRCA2 (n = 12), sporadic (n = 26)	3.5 k BAC	1	[58]
1 Case report	1777 BAC	~1.5	[66]
24 pairs LCIS + ILC	~2400 BAC	1.5	[68]
4 synchronous tumours (2 BC and 2 leiomyosarcomas)	2.5 k BAC	1.5	[70]
BC cell line (n = 1)	6 k BAC	<1	[93]
11 BC cell lines	2464 BAC (Hum-Array1.14)	1.5	[95]
52 node-negative invasive BC	57 oncogene loci (AmpliOnc™)		[96]
Premenopausal BC and radiation (n = 47)	3.5 k BAC	1	[107]
16 cell lines (8 of them BC)	9862 SNPs		[108]
2 BC cell lines	2560 BAC	1.5	[109]
47 fresh-frozen IDC BC	4134 BAC	0.9	[110]

BAC, bacterial artificial chromosome; BC, breast cancer; CGH, comparative genomic hybridization; FFPE, formalin-fixed paraffin-embedded; IDC, invasive ductal carcinoma; ILC, invasive lobular carcinoma; LCIS, lobular carcinoma in situ; SNP, single nucleotide polymorphism.