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Cefepime population pharmacokinetic parametersa
| Parameter | V1 (liters) | Kcp (h−1) | Kpc (h−1) | CLi (liters/h) | CLs |
|---|---|---|---|---|---|
| Mean | 22.97 | 11.20 | 35.63 | 0.389 | 0.0628 |
| Median | 27.08 | 12.58 | 41.09 | 0.329 | 0.0551 |
| SD | 15.56 | 8.069 | 19.48 | 0.354 | 0.0324 |
CL = CLi + (CLs × CLCR). Kcp, rate constant from the central compartment to the peripheral compartment; Kpc, rate constant from the peripheral compartment to the central compartment.
