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CYP71A10-mediated metabolism of phenylurea herbicides. Shown are thin-layer chromatograms of 14C-radiolabeled fluometuron, linuron, chlortoluron, and diuron and their respective metabolites after incubation of the radiolabeled herbicides with yeast microsomes containing the CYP71A10 protein. Initial substrate concentrations for fluometuron, linuron, chlortoluron, and diuron were 5.2, 6.5, 4.0, and 3.7 μM, respectively. P, parent compound; M, metabolite.
