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. 2003 Jun;47(6):1912–1921. doi: 10.1128/AAC.47.6.1912-1921.2003

FIG. 3.

FIG. 3.

IFN and ribavirin induce DEVDase activity in HepG2 cells. Lysates of HepG2 cells were assayed with DEVD-AMC after incubation for 24 h with the indicated stimuli. The slope of the AMC release was measured fluorometrically and expressed as fold AMC release in unstimulated cells. (A) IFN only; (B) ribavirin only; (C) 10 kU of IFN per ml plus ribavirin as indicated on the x axis; (D) 100 kU of IFN per ml plus ribavirin as indicated on the x axis. Values are means and standard deviations of triplicate determinations. Representative plots from two independent experiments are shown.