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. 2003 Jun;47(6):1912–1921. doi: 10.1128/AAC.47.6.1912-1921.2003

FIG. 6.

FIG. 6.

Pretreatment with IFN and ribavirin enhances anti-CD95-induced caspase-3 activation. Representative photomicrographs of HepG2 cells following stimulation with 0.25 μg of anti-CD95 per ml for 4 h and subsequent immunocytochemical detection of active caspase-3 are shown. (A) No pretreatment. (B) Pretreatment with 105 U of IFN per ml for 24 h. (C) Pretreatment with 103 μM ribavirin for 24 h. (D) Pretreatment with 105 U of IFN per ml plus 103 μM ribavirin for 24 h.