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. 2003 Jun;47(6):1979–1983. doi: 10.1128/AAC.47.6.1979-1983.2003

TABLE 2.

Prevention of S. aureus infection using RIP-coated Dacron grafts in the presence or absence of local antibiotic prophylaxis

Antibiotic(s) Bacterial concn (log CFU/ml [mean ± SD])a
MRSA MSSA
Control (untreated) 7.73 ± 0.11 7.49 ± 0.07
RIP 4.52 ± 0.09b,c 4.64 ± 0.06b,c
Mupirocin 2.91 ± 0.16b 2.84 ± 0.17b
Mupirocin + RIP <1b,d,e <1b,d,e
Rifampin 4.85 ± 0.15b 4.92 ± 0.14b
Rifampin + RIP 2.96 ± 0.09b,f 3.57 ± 0.04b
Quinupristin-Dalfopristin 1.68 ± 0.08b 1.64 ± 0.19b
Quinupristin-Dalfopristin + RIP <1b,e <1b,e
Levofloxacin 5.9 ± 0.15b 4.89 ± 0.14b
Levofloxacin + RIP 4.18 ± 0.19b,g 3.93 ± 0.09b
a

n = 15 rats per group.

b

P < 0.05 versus untreated control group.

c

P < 0.05 versus mupirocin treatment, and Quinipristin-dalfopristin treatment.

d

P < 0.05 versus mupirocin treatment.

e

P < 0.05 versus levofloracin-RIP treatment and rifampin-RIP treatment.

f

P < 0.05 versus rifampin treatment.

g

P < 0.05 versus levofloxacin treatment.

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