TABLE 1.
Effect of 7 days of oral treatment of human volunteers with either amoxiclav (1 g of amoxicillin and 125 mg of clavulanic acid 3 times/day) or telithromycin (800 mg 1 time/day) on the prevalence of fecal yeast colonization (25 volunteers/treatment group)
| Day | No. (%) of subjects colonized before or after treatment with:
|
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Amoxiclav
|
Telithromycin
|
|||||||||
| Any yeasta | Candida albicans | Other Candida sp. | Geotricum | Other | Any yeasta | Candida albicans | Other Candida sp. | Geotricum | Other | |
| −1 | 7 (28) | 5 (20) | 2 (8)b | 7 (28) | 0 | 8 (32) | 4 (16) | 2 (8)c | 4 (16) | 0 |
| 8 | 14 (56) | 11 (45) | 4 (16)d | 2 (8) | 3 (12)o | 15 (60) | 8 (32) | 2 (8)e | 6 (24) | 3 (12)f |
| 14 | 13 (52) | 8 (32) | 1 (4)g | 10 (40) | 0 | 14 (56) | 9 (36) | 2 (8)h | 9 (36) | 1 (4)i |
| 21 | 12 (48) | 10 (40) | 2 (8)j | 6 (24) | 0 | 9 (36) | 7 (28) | 1 (4) | 4 (16) | 1 (4)k |
| 45l | 13 (54) | 7 (29) | 2 (8)m | 10 (42) | 1 (4) | 9 (38) | 7 (29) | 2 (8)n | 5 (21) | 0 |
Some volunteers were colonized by multiple species.
C. tropicalis, 1 subject; C. krusei, 1 subject.
C. lusitaniae, 1 subject; C. glabrata, 1 subject.
C. tropicalis, 1 subject; C. Kefyr, 1 subject; C. krusei, 1 subject.
C. norvegensis, 1 subject; C. glabrata, 1 subject.
Trichosporon, 2 subjects; Rhodotorula rubra, 1 subject.
C. tropicalis, 1 subject.
C. glabrata, 2 subjects.
R. rubra, 1 subject.
C. kefyr, 1 subject; C. krusei, 1 subject.
R. rubra, 1 subject.
There were 24 volunteers in each treatment group only.
C. kefyr, 1 subject; C. inconspicua, 1 subject.
C. krusei, 1 subject; C. glabrata, 1 subject; C. candida sp., 1 subject.
Saccharomyces cerevisiae, 3 subjects.