TABLE 2.
Effects of 7 days of oral treatment of human volunteers with either amoxiclav (1 g of amoxicillin and 125 mg of clavulanic acid 3 times/day) or telithromycin (800 mg 1 time/day) on the prevalence of cutaneous colonization by CNS (25 volunteers/treatment group)
| Day | No. (%) of subjects colonized before or after treatment with:
|
|||||||
|---|---|---|---|---|---|---|---|---|
| Amoxiclav
|
Telithromycin
|
|||||||
| Any CNS | CNS with DS to:
|
Any CNS | CNS with DS to:
|
|||||
| Erythro- mycin | Methi- cillin | Telithro- mycin | Erythro- mycin | Methi- cillin | Telithro- mycin | |||
| −1 | 21 (84) | 6 (25) | 1 (4) | 1 (4) | 18 (72) | 5 (20) | 1 (4) | 0 |
| 8 | 19 (76) | 7 (28) | 3 (12) | 1 (4) | 16 (64) | 6 (24) | 0 | 2 (8) |
| 45a | 18 (75) | 9 (38) | 2 (8) | 0 | 20 (83) | 10 (42) | 2 (8) | 5 (21) |
a
There were 24 volunteers only in each treatment group.