TABLE 3.
Influence of 7 days of oral treatment of human volunteers with either amoxiclav (1 g of amoxicillin and 125 mg of clavulanic acid 3 times/day) or telithromycin (800 mg 1 time/day) on the prevalence of oral colonization by NGS (25 volunteers/treatment group)
Day | No. (%) of subjects colonized before or after treatment with:
|
|||||||
---|---|---|---|---|---|---|---|---|
Amoxiclav
|
Telithromycin
|
|||||||
Any NGS | NGS with DS to:
|
Any NGS | NGS with DS to:
|
|||||
Erythro- mycin | Amoxi- cillin | Telithro- mycin | Erythro- mycin | Amoxi- cillin | Telithro- mycin | |||
−1 | 25 (100) | 24 (96) | 7 (28) | 20 (80) | 25 (100) | 25 (100) | 5 (20) | 14 (56) |
8 | 25 (100) | 25 (100) | 24 (96) | 16 (64) | 25 (100) | 25 (100) | 6 (24) | 25 (100) |
45a | 24 (100) | 24 (100) | 19 (79) | 19 (79) | 24 (100) | 24 (100) | 7 (29) | 22 (92) |
There were 24 volunteers in each treatment group only.