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. 2003 Jun;47(6):1790–1797. doi: 10.1128/AAC.47.6.1790-1797.2003

TABLE 3.

Prevalence of MDR phenotypes in S. pneumoniae isolated from patients in different age groups in the United States from 2000 to 2002

Patient age (yr) No. of isolates tested No. (%) of isolates with an MDR phenotypea % of MDR isolates with the most prevalent MDR phenotypeb No. (%) of MDR isolates that included levofloxacin resistance % of all isolates that were MDR and resistant to levofloxacin
<2 1,080 283 (26.1) 75.3 0 (0) 0
2-4 797 192 (24.1) 70.8 1 (0.5) 0.1
5-10 611 84 (13.7) 71.4 1 (1.2) 0.2
11-17 346 41 (11.9) 70.3 0 (0) 0
18-64 6,339 767 (12.1) 74.6 25 (3.3) 0.4
>64 4,627 573 (12.4) 76.6 22 (3.8) 0.5
a

Resistance to three or more of the following antimicrobial agents: penicillin, ceftriaxone, azithromycin, SXT, and levofloxacin (19).

b

The most prevalent MDR phenotype consisted of resistance to penicillin, azithromycin, and SXT. For all age groups, this phenotype included ceftriaxone-intermediate isolates five to seven times more frequently than ceftriaxone-susceptible isolates.