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Concentrations of vancomycin and teicoplanin in the sera of three uninfected rabbits after the intramuscular administration of a single antibiotic dose
| Regimen (dose [mg/kg]) | Concn (μg/ml) in serum (time [h])
|
|
|---|---|---|
| Peak | Trough | |
| Vancomycin (40) | 39 ± 12 (2) | 12 ± 3 (12) |
| Vancomycin (50) | 45 ± 8 (2) | 20 ± 5 (8) |
| Teicoplanin (20) | 44 ± 5 (4) | 24 ± 1 (12) |
| Teicoplanin (40) | 95 ± 17 (4) | 59 ± 21 (12) |
