Table 1.

CD4⁺ T cell numbers, subsets, and virus load at moment of analysis

Patient*	Moment of analysis, mo†	Serostatus‡	CD4+ T cells/μl blood	CD45RO+ CD4+ T cells, %	CD45RA+ CD4+ T cells, %	Frequencies of infected cells (TCID/104 cells)
						CD4+ T cells§	CD45RO+ CD4+ T cells	CD45RA+ CD4+ T cells¶
N1	151	1	400	58	28	5	22	<2 (dl)
N2	103	1	240	71	16	269	709	11
N3	148	2	440	33	58	191	434	9
N4	22	2	380	30	61	34	115	4
N5	60	2	750	39	54	111	431	6
N6	103	2	530	45	48	20	38	1
N7	64	1	1020	47	45	53	178	4
N8	7	1	1060	37	42	2	2	<2 (dl)
S1	100	2	330	63	17	340	431	53
S2	74	2	320	69	15	81	77	25
S3	117	2	430	51	14	361	420	212
S4	104	1	280	63	20	142	380	41
S5	148	2	260	44	40	NT	68	190
S6	100	1	310	52	35	160	220	164
S7	148	2	70	85	9	42	109	<19 (dl)
S8	37	2	380	52	35	297	701	874
S9	120	1	540	28	67	5	3	4
S10	46	2	460	42	48	13	1	18
S11	94	1	290	39	37	103	282	39
S12	35	1	820	35	43	25	74	9

^*N, patient with only NSI variants; S, patient with both SI and NSI variants; for two patients a time point before and a time point after SI switch were analyzed; N7 − S11 and N8 − S12. 

^† Months after seroconversion or seropositive entry in the Amsterdam Cohort Studies (ACS). 

^‡ HIV-1 serostatus at the moment of entry in the ACS: 1, participants who were seronegative at entry in the ACS, and seroconversion date was estimated to be the midpoint between the last HIV-1⁻ and the first HIV-1⁺ visit; 2, participants who were already seropositive at entry in the ACS. 

^§ NT, not tested. 

^¶ dl, detection limit of the assay.