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. 2006 Aug 29;398(Pt 3):319–337. doi: 10.1042/BJ20060450

Figure 6. Potential functions of RecQ helicases at replication forks.

Figure 6

Biochemical and cellular studies have suggested that RecQ helicases act upon certain DNA structural intermediates at the replication fork to ensure accurate processing and genome fidelity. RecQ helicases may act upon the replication fork in various capacities (resolution of secondary structures, lagging strand processing, branch fork migration, DNA-damage sensing or bypass, replication fork regression and WRN proofreading function). See the text for details.