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. 2006 Aug 29;398(Pt 3):509–514. doi: 10.1042/BJ20060566

Figure 3. Plasma pharmacokinetics of hypodermic NAC.

Figure 3

Plasma levels of NAC and cysteine after hypodermic injection of 1 g of NAC/kg body weight were monitored over 24 h using the HPLC method shown in Figure 2. The maximal concentration of NAC is observed at 2 h from injection (A); interestingly, after 8 h, NAC is present only in trace amount, indicating that NAC is rapidly removed from the bloodstream. A slight increase in the plasma level of cysteine was observed after 4 h; however, differences were not statistically significant (B). Results are expressed as means±S.D. (n=4).