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Histograms of the distribution of MLH1 on chromosomal bivalent 22. The X-axis indicates the position (in μm) of MLH1 foci along the length of the bivalent. The position of the centromere is indicated by a small blackened circle; the p arm lies to the left, and the q arm lies to the right. The Y-axis indicates the number of MLH1 foci mapped to each interval. A, Distribution of MLH1 on bivalents with only one focus. B, Distribution of MLH1 on bivalents with two foci.
