Table 5. .

Ensembl Genes and Fetal Brain Gene Expression in Regions Defined by de Novo CNVs in Children with Idiopathic MR^[Note]

							SAGE Tag Expression Bins
Family	De Novo CNV	Chromosome	Starting Breakpoint (bp)	Ending Breakpoint (bp)	No. of Ensembl Gene Predictions in Region	No. of Genes Mapped by SAGE Tags	1–5	6–9	10–49	50–99	100+	Total Tags	Total Tags in Genes
1895	Deletion	13	18867056	24517730	63	16	70	20	6	1	0	97	45
3476	Deletion	4	82146749	93214433	112	22	113	29	15	8	4	169	57
4794	Duplication	16	925718	3864938	165	47	109	43	33	11	10	206	102
4818	Deletion	12	63342649	66780095	29	9	31	9	9	0	0	49	22
5003	Deletion	2	50857428	51178791	0	0	9	3	0	0	0	12	0
5566	Deletion	14	20741117	20918741	3	0	1	1	1	0	0	3	0
5994a	Mosaic trisomy	9	…	…	1,362	433	1,085	344	284	50	23	1,786	1,113
6168	Duplication	17	45093545	46196038	37	12	47	15	15	5	1	83	32
6545	Deletion	7	3304850	6940933	73	15	56	20	20	2	2	100	43
7807	Deletion	22	26138764	27552525	17	3	31	7	3	0	0	41	12
8326	Deletion	14	19584863	21207935	72	12	34	11	11	2	1	59	26

Note.— Expression levels were estimated by the number of unique tag types per expression level bin (normalized to tags per million) in long SAGE Library LSAGE_Brain_fetal_normal_B_S.

^aStarting and ending breakpoints are not shown because CNV involves the whole chromosome.