Table 1. .
Subject | Sex | Age at Death (years) |
BMIa | Medical History and Autopsy Finding(s) |
1 | Fb,c | 49 | 40.3 | Cardiovascular disease, lung disease, and hyperthyroidism |
2 | Fb,c,d | 49 | 39.1 | Cardiovascular disease and kidney failure |
3 | Fd | 58 | 60.6 | Lung disease |
4 | Fc | 60 | 21.7 | Thyroid adenoma and brain tumor |
5 | Mc,d | 64 | 35.4 | Cardiovascular disease and pulmonary edema |
6 | Mb | 67 | 27.6 | Diabetes, nephropathy, and cardiovascular disease |
7 | Mb,c | 76 | 23.1 | Cardiovascular disease and nephropathy |
8 | Mc,d | 79 | 21.9 | Cardiovascular disease and lung disease |
9 | Fb,c,d | 83 | 32.0 | Cardiovascular disease |
10 | Mb | 92 | NA | Cardiovascular disease, lung disease, and dementia |
11 | Fb,c,d | 92 | 18.7 | Cardiovascular disease and leukemia |
12 | Fc,d | 93 | 22.0 | Cardiovascular disease and nephropathy |
BMI = weight (in kg)/height2 (in cm); ⩽18.5 = underweight; 18.5–24.99 = normal weight; 25–29.99 = overweight; ⩾30.0 = obese. NA = data not available.
Tissue was used for individual ETS-abnormal fiber analysis.
Tissue was used for mtDNA4977 homogenate analysis.
Tissue was used for mtDNA7664 homogenate analysis.