Figure 3.

Histological alterations of the pancreas from MT-tgfα/Ela-myc double transgenic mice. A: multilocular cystic neoplasms mixed with acinar tumor cells (arrows). B: a large benign multilocular cystic neoplasm. C: a typical acinar cell carcinoma. D: one type of ductal adenocarcinoma. E: another type of ductal adenocarinoma. F: a much less differentiated ductal adenocarcinoma with feature of desmoplasia. G: a mixed acinar and ductal adenocarcinoma. H: an area showing feature of mouse PanIN3 or ductal adenocarcinomas (dark arrows) with acinar tumor cells (yellow arrows) in the surrounding. I: a tumor area showing squamous differentiation.