Table 1.
Effect of increased peak inspiratory pressure on ventilation, FRC and ventilatory inhomogeneity indices in 15 ventilated piglets (Presented are groups means ± SD and the mean individual changes with 95%CI compared to the baseline)
| Baseline | Increased peak inspiratory pressure | Mean individual difference in % with 95%CI | P value | |
| VT (mL) | 15.4 ± 9.5 | 21.9 ± 14.7 | 38.9 (20.4 to 57.45) | p = 0.003 |
| FRC (mL) | 31.6 ± 14.7 | 35.0 ± 15.9 | 11.1 (4.5 to 17.8) | p = 0.006 |
| VT/FRC | 0.48 ± 0.17 | 0.59 ± 0.20 | 25.0 (10.7 to 39.4) | p = 0.003 |
| VD/VT | 0.49 ± 0.15 | 0.43 ± 0.13 | -10.2 (-21.0 to 0.5) | p = 0.006 |
| LCI | 9.17 ± 0.75 | 8.55 ± 0.74 | -6.4 (-11.8 to -1.0) | p = 0.019 |
| M1/M0 | 2.03 ± 0.16 | 1.84 ± 0.16 | -9.4 (-14.0 to -4.9) | p = 0.006 |
| M2M0 | 8.41 ± 1.60 | 7.22 ± 4.80 | -12.1 (-23.1 to -1.4) | p = 0.017 |
| AMDN1 | 1.034 ± 0.30 | 1.028 ± 0.19 | -0.6 (-9.1 to 7.9) | p = 0.886 |
| AMDN2 | 2.88 ± 1.56 | 3.01 ± 1.06 | 4.5 (-9.9 to 18.1) | p = 0.515 |