Table 1.
Ala10 sequences | [θ]222 |
---|---|
1. W-K4-Inp2-tL-A10-tL-Inp2-K4-NH2 | +400 |
2. W-K4-Inp2-a-A10-A-Inp2-K4-NH2 | −2100 |
3. W-R4-Inp2-a-A10-A-Inp2-R4-NH2 | −1500 |
Ala12 sequences | [θ]222 |
---|---|
4. W-K4-Inp2-tL-A12-tL-Inp2-K4-NH2 | −3900 |
5. W-K4-tL2-tL-A12-tL-tL2-K4-NH2 | −2400 |
Ala15 sequences | [θ]222 |
---|---|
6. W-K4-Inp2-tL-A15-tL-Inp2-K4-NH2 | −15 400 |
7. W-K4-tL2-tL-A15-tL-tL2-K4-NH2 | −15 500 |
8. W-K4-Aze2-tL-A15-tL-Aze2-K4-NH2 | −16 700 |
9. W-K4-Inp2-tL-A15-A-Inp2-K4-NH2 | −17 200 |
10. W-K4-Inp2-a-A15-tL-Inp2-K4-NH2 | −17 700 |
11. W-K4-Inp2-a-A15-A-Inp2-K4-NH2 | −21 100 |
Per-residue ellipticity data, deg cm2 dmol−1, are cap-corrected as previously reported.3b
tL, tert-leucine; Inp, 4-carboxypiperidine; Aze, azetidine-3-carboxylic acid; a, d-alanine.