Table 7.
Comparison of Campylobacter coverage bias. Kolmogorov-Smirnov comparison of the distributions of reads per bin from an unamplified sample of Campylobacter jejuni with an additional unamplified replicate library and libraries amplified with GenomiPhi, Repli-G, PEP and DOP. Bin Size refers to the number of bases comprising each individual bin into which the genome was broken for analysis; 100,000 reads were used for each analysis. Ranked bias was derived from ranked D statistics, lowest to highest.
| Unamplified Control versus: | Unamplified Replicate | GenomiPhi | RepliG | PEP | DOP |
| Bin Size (bp) | 10 | ||||
| Number of Bins | 164149 | ||||
| Number of Reads | 100000 | ||||
| D Statistic | 0.001 | 0.034 | 0.029 | 0.122 | 0.392 |
| P value | 1.000 | 0.000 | 0.000 | 0.000 | 0.000 |
| Ranked Bias (5 is lowest) | 5 | 3 | 4 | 2 | 1 |
| Bin Size (bp) | 100 | ||||
| Number of Bins | 16415 | ||||
| Number of Reads | 100000 | ||||
| D Statistic | 0.004 | 0.060 | 0.079 | 0.247 | 0.882 |
| P value | 0.997 | 0.000 | 0.000 | 0.000 | 0.000 |
| Ranked Bias (5 is lowest) | 5 | 4 | 3 | 2 | 1 |
| Bin Size (bp) | 1641 | ||||
| Number of Bins | 1001 | ||||
| Number of Reads | 100000 | ||||
| D Statistic | 0.028 | 0.214 | 0.275 | 0.483 | 0.915 |
| P value | 0.814 | 0.000 | 0.000 | 0.000 | 0.000 |
| Ranked Bias (5 is lowest) | 5 | 4 | 3 | 2 | 1 |
| Bin Size (bp) | 16413 | ||||
| Number of Bins | 100 | ||||
| Number of Reads | 100000 | ||||
| D Statistic | 0.074 | 0.248 | 0.307 | 0.505 | 0.842 |
| P value | 0.922 | 0.004 | 0.000 | 0.000 | 0.000 |
| Ranked Bias (5 is lowest) | 5 | 4 | 3 | 2 | 1 |