Figure 2. K5-PKCα mice have increased circulating levels of MIP-2 and KC in response to TPA painting.

A single dose of TPA (1 μg) in acetone was applied to the shaved backs of K5-PKCα transgenic and WT littermates, blood was drawn at various times, and ELISA for KC and MIP-2 was performed on sera. Bars represent the mean ± SEM for 6 animals, and results are representative of at least 2 independent experiments. *P < 0.05 versus the respective control.