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. 2003 May 15;31(10):2544–2552. doi: 10.1093/nar/gkg355

Table 1. Levels of human transcript coverage versus extent of conservation in mouse.

Human transcript coveragea,b Fraction of considered human splice junctions that are conserved in mousec
  All splice junctions (constitutive and alternative) Constitutive splice junctions Alternative splice junctions
1 0.173 0.492 0.082
2 0.366 0.594 0.165
3 0.526 0.664 0.337
4 0.574 0.710 0.327
5–9 0.629 0.723 0.326
≥10 0.749 0.779 0.530

aOnly 19% of constitutive splice junctions as opposed to 64% of alternative splice junctions have transcript coverage of 1. As high as 51% of constitutive splice junctions as opposed to 10% of alternative splice junctions have a high transcript coverage of ≥5.

bThe extents of conservation of splice junctions, irrespective of the human transcript coverage, is 41% for all 2932 (constitutive and alternative) splice junctions, 67% for the 1440 constitutive splice junctions, and 15% for the 1492 alternative splice junctions.

cThe extent of conservation increases with the increasing human transcript coverage, irrespective of the type of splice junction (constitutive or alternative).