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. 2003 May 15;31(10):2683–2693. doi: 10.1093/nar/gkg356

Figure 1.

Figure 1

Figure 1

NMR spectra of the propyne-modified DNA·RNA hybrid duplex. Spectra were recorded at 303 K and 600 MHz as described in the Materials and Methods. (A) NOESY spectrum recorded with a mixing time of 250 ms. The base-H1′ region is shown, with connectivities of the DNA and RNA strands. Red, RNA purine strand; cyan, modified DNA pyrimidine strand; green, Ade H2 intra and cross-strand NOEs. (B) Double quantum filtered COSY spectrum of the H1′ to H2′/H2” region showing the coupling patterns for the deoxyriboses. The acquisition time in t2 was 0.68 s.