Table 2.
Risk of dying in relation to primary cause of death. Cox regression, Hazard Risk ratio* and 95 % confidence interval.
| All deaths | Respiratory | Cardiovascular | |
| Age (10 years) | 1.49 (1.17–1.90) | 1.45 (1.07–1.97) | 2.62 (1.35–5.10) |
| Women | 0.67 (0.44–1.03) | 0.70 (0.41–1.21) | 0.89 (0.32–2.48) |
| Current smoking | 1.47 (0.91–2.38) | 1.73 (0.97–3.10) | 0.93 (0.18–4.86) |
| FEV1 (per 10% pred. change) | 0.83 (0.71–0.96) | 0.76 (0.62–0.92) | 0.87 (0.61–1.25) |
| ≥ 2 previous hospitalizations | 1.22 (0.79–1.90) | 1.33 (0.77–2.30) | 1.35 (0.43–4.22) |
| SGRQ score (4 units) | |||
| Symptoms** | 1.04 (0.99–1.09) | 1.03 (0.96–1.10) | 1.06 (0.95–1.17) |
| Activity** | 1.03 (0.98–1.08) | 0.99 (0.93–1.04) | 1.12 (0.98–1.28) |
| Impact** | 1.06 (1.01–1.11) | 1.07 (1.00–1.14) | 1.09 (0.97–1.22) |
| Total score | 1.07 (1.01–1.14) | 1.05 (0.97–1.14) | 1.14 (0.99–1.32) |
| Co-morbidities | |||
| Diabetes | 2.25 (1.28–3.95) | 2.42 (1.18–4.96) | 3.82 (1.15–12.8) |
| Cardio-vascular disease | 1.43 (0.92–2.23) | 1.52 (0.87–2.65) | 1.96 (0.65–5.92) |
| COPD severity according to the GOLD classification (12)*** | |||
| GOLD stage I-II | 1 | 1 | 1 |
| GOLD stage III | 1.18 (0.63–2.20) | 1.09 (0.46–2.57) | 0.69 (0.16–2.88) |
| GOLD stage IV | 1.81 (1.02–3.24) | 2.40 (1.13–5.12) | 1.05 (0.27–4.06) |
* adjusted for centre and the variables in the table
** entered separately, replacing SGRQ or HAD total score
*** entered separately, replacing FEV1