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. 2003 May 1;22(9):1990–2003. doi: 10.1093/emboj/cdg197

Table V. Correlation between the presence of the H-bond between loops B and C and the potency in wild-type and mutant receptors.

 
% H-bonda
Potency
α4β2 42 High
α7 0 Low
α7 G152K 14 High
α7 P193I 0 High
α7 G152K/P193I 20 High
α1β1γδ 0 Low
α1β1γδ α1G153S 39 High

aDetermined as the number of recorded conformers that displayed the H-bond relative to the total number of recorded conformers.