Table II. X chromosome instability in females (F) or males (M) of different genotypes.
Sex | Genotype | No. of cells | (nX) | (nX) + X | (nX) – X | (nX) + derX |
---|---|---|---|---|---|---|
Female | parp-1+/+parp-2–/– | 30 | 29 | 0 | 1 | 0 |
Female | parp-1–/–parp-2+/+ | 21 | 21 | 0 | 0 | 0 |
Male | parp-1+/–parp-2–/– | 35 | 35 | 0 | 0 | 0 |
Female | parp-1+/–parp-2–/– | 132 | 66 | 19 | 33 | 14 |
(nX) = metaphases with normal number of X chromosomes: XX, for female, X for male; (nX) + X = metaphases with one X in surplus; (nX) – X = metaphases with one X missing; (nX) + derX = metaphases with any kind of X aneuploidy and a derivative of X chromosome.