FIG. 5.

Effect of SWI/SNF on repair of three different lesions in mononucleosomes. Nucleosomal DNAs (30 pM) were incubated with reconstituted excision nuclease in the absence or presence of SWI/SNF (0.48 nM) for the indicated times, and the reaction products were separated on 8% polyacrylamide gels. The top panels show representative autoradiograms of excision gels. In the bottom panel the level of excision as percentage of input substrates is plotted from three independent experiments; the bars indicate standard errors.