FIG. 4.

Transmission electron microscopy of SIV-infected primary macaque astrocytes. (A) Low magnification of astrocyte cultures infected with SIV/17E-Fr and allowed to incubate for 14 days before samples were prepared as described in Materials and Methods and sent to Electron Microscopy Bioservices for analysis. Bar, 1 μm. (B) Higher magnification of the cell shown in panel A, showing SIV budding from the plasma membrane. Bar, 0.2 μm. B, budding virions; M, mature particle; I, intermediate filaments.