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AOP-RANTES blocks SIV infection of primary rhesus astrocytes. Astrocytes were incubated with or without 500 ng of AOP-RANTES per ml for 1 h prior to infection with SIV/17E-Br or SIV/17E-Fr [input virus normalized by TCID50 (multiplicity of infection = 0.1)], and supernatants were sampled at various times postinfection (PI) and assayed for the presence of SIV p27. Data are representative of several independent experiments.
