TABLE 1.
Specimena | Age (yr)/sexb | Cause of death | Time from death to autopsy (h)g | Results for:
|
|||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Neurons
|
Satellite cells
|
||||||||||
No. of tubes testedd | No. of cells tested | No. positive | Latent % of fractionh | No. of tubes tested | Total no. of clumps | Total no. of cellse | No. positive | ||||
HG-70 | 71/M | CHFc | 6 | 2 | 26 | 1 | 3.8 | 13 | 46 | 2,484 | 0 |
HG-76 | 90/F | Pneumonia | 3 | 34 | 340 | 4 | 1.2 | 18 | 38 | 2,052 | 0 |
HG-79 | 49/F | Carcinoma | 14 | 22 | 220 | 6 | 2.7 | 18 | 90 | 4,860 | 0 |
HG-82 | 85/M | Lymphoma | 16 | 22 | 220 | 2 | 0.9 | 6 | 30 | 1,620 | 0 |
HG-83 | 64/M | Alzheimer's | Unknown | 12 | 120 | 1 | 0.8 | NDf | |||
HG-88 | 66/M | Chronic leukemia | 15 | 18 | 180 | 3 | 1.7 | 18 | 90 | 4,860 | 0 |
HG-91 | 72/M | Peritonitis | 21 | 22 | 220 | 3 | 1.4 | 18 | 90 | 4,860 | 0 |
HG-93 | 28/M | Lymphoma | 18 | 18 | 180 | 4 | 2.2 | ND | |||
HG-95 | 66/F | CHF | 6 | 18 | 180 | 2 | 1.1 | ND | |||
HG-97 | 44/M | Cystic fibrosis | 22 | 18 | 180 | 3 | 1.7 | ND | |||
HG-100 | 59/M | CHF/diabetes | 16 | 18 | 180 | 3 | 1.7 | ND | |||
HG-101 | 61/M | Chronic leukemia | 20 | 18 | 180 | 2 | 1.1 | ND | |||
Total | 222 | 2,226 | 34 | 91 | 384 | 20,736 | 0 |
A fragment of each ganglion was demonstrated by PCR to contain VZV DNA prior to cell separation. Serum from each autopsy contained VZV-specific antibody.
Numbers indicate age at death (average, 62.9 years). M, male; F, female.
CHF, congestive heart failure.
Contained 10 neurons per tube except for HG-70 (10 and 16 cells).
Each clump of satellite cells contained a mean of 54 cells (21).
ND, not done.
Average, 14.3 h.
Average ± standard deviation, 1.7% ± 0.86%.