FIG. 10.

Membrane-proximal region of the interface between monomers in the HN dimer. The domain targeted for mutagenesis in this study is shown for both monomers in a dimer. The membrane view shows the antiparallel orientation of the two domains. Hydrogen bonds are indicated by dotted lines. The figure was generated from the pH 6.5 structure of the HN of the L-Kansas NDV isolate with Swiss PDB-Viewer (Glaxo Wellcome Experimental Research). Note that residue 219, an isoleucine in NDV-L HN, is a valine in NDV-AV HN.