FIGURE 6.

Contacts (<4 Å) between residues of the Mlc1p protein and the bound IQ peptides obtained from the MD simulations at t > = 6 ns. Data regarding the Mlc1p-IQ4 structure simulation (60) are presented at the upper half of the illustration, whereas data regarding the Mlc1p-IQ2 structure simulation are presented at its lower half. The IQ peptides, the N-lobe of the protein, the interdomain of the protein, and the C-lobe of the protein are colored in black, blue, red, and green, respectively. Residues of the Mlc1p protein that interact with both peptides are underlined. Only contacts that persist at least 80% of the examined period are presented.