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Phases in DOPC/Chol 1:1 mixtures, 10% (w/v) in PBS, at 20°C. (A) Initial lamellar phase Lα with spacing d = 6.57 nm. (B—D) Cubic phase patterns. (B) Im3m phase with lattice parameter of 32.3 nm obtained with the temperature protocol shown in Fig. 1 B. (C) Im3m phase (26.6 nm) with admixture of Pn3m phase (20.7 nm). (D) Im3m (30.1 nm) obtained after incubation at 76°C. No intensity adjustments have been made.
