TABLE 2.

Bacteriological data and clinical outcome for CDAD patients who were treated with fusidic acid and were culture positive for C. difficile on day 1 and later

Patient	Fusidic acid MIC (mg/liter) on day(s)a,b:			PCR ribotype (SE) on day(s)b:			Outcome on day(s)c:
	1	8-13	35-40	1	8-13	35-40	8-13	35-40
1	0.25	>256	>256	22	22	22	+
2	0.38	0.25	>256	19c	19c	19c		+
3	0.38	>256		25	25
4	0.75		>256	21a		21a
5	0.38	1	4	7	43	43
6	0.75	>256		21b	21b		+
7	0.5	24	0.25	16	16	41		+
8	0.75	48		12	12		+
9	0.75	32		57	57
10	0.125		48	29b		29b		+
11	0.125		>256	17		17
12	0.5	0.38		12	12		+
13	0.25		0.5	16e		29b		+
14	0.38	0.25		30	30
15	0.25	0.25	0.25	25	25	25		+
16	0.25		0.19	1		19		+
17	0.25		0.25	16		16
18	0.19		0.125	21		21
19	0.125	0.25		28	28
20	0.25		0.25	21b		2

^aThe fusidic acid MIC was >256 mg/liter for 1 pretreatment isolate of 88 (metronidazole group). The metronidazole MICs of all the above and other isolates tested (n = 139) were <1 (median, 0.125; range, 0.016 to 0.5) mg/liter.

^bAn empty cell indicates that the patient was culture negative for C. difficile on that occasion.

^cDiarrhea at follow-up is indicated by a plus sign.