TABLE 1.
MICs for in vitro susceptibilities of four Candida species to recombinant scFv anti-idiotypic antibodiesa
| Candida strain | MIC (μg/ml) of:
|
|||
|---|---|---|---|---|
| scFv-A1 | scFv-A2 | scFv-A3 | scFv-A4 | |
| C. albicans ATCC 10231 | 6.25 | 3.13 | 3.13 | 6.25 |
| C. albicans NBRC 0197 | 6.25 | 3.13 | 6.25 | 3.13 |
| C. albicans NBRC 0759 | 6.25 | 3.13 | 6.25 | 6.25 |
| C. albicans NBRC 1389 | 6.25 | 3.13 | 6.25 | 6.25 |
| C. albicans NBRC 1390 | 6.25 | 3.13 | 6.25 | 3.13 |
| C. albicans NBRC 1392 | 6.25 | 3.13 | 6.25 | 3.13 |
| C. albicans NBRC 1397 | 12.5 | 6.25 | 6.25 | 12.5 |
| C. albicans NBRC 1856 | 12.5 | 6.25 | 6.25 | 12.5 |
| C. albicans NBRC 1974 | 6.25 | 3.13 | 6.25 | 6.25 |
| C. albicans IFM 40213 | 6.25 | 3.13 | 6.25 | 3.13 |
| C. tropicalis NBRC 1400 | 6.25 | 3.13 | 6.25 | 3.13 |
| C. parapsilosis NBRC 1396 | 6.25 | 3.13 | 6.25 | 6.25 |
| C. glabrata NBRC 0622 | 3.13 | 1.56 | 3.13 | 1.56 |
a
The measurement of MICs for the cell growth of the Candida species is described in Materials and Methods.