TABLE 2.
IC50 values for recombinant scFv anti-idiotypic antibodies against the cell growth of four Candida speciesa
| scFv antibody | IC50 (10−8 M) for:
|
|||
|---|---|---|---|---|
| C. albicans ATCC 10231 | C. tropicalis NBRC 1400 | C. parapsilosis NBRC 1396 | C. glabrata NBRC 0622 | |
| ScFv-A1 | 12.7 | 16.0 | 14.0 | 11.3 |
| ScFv-A2 | 7.3 | 8.7 | 8.3 | 8.0 |
| ScFv-A3 | 8.7 | 15.7 | 15.0 | 9.7 |
| ScFv-A4 | 11.7 | 9.3 | 12.3 | 8.8 |
a
The measurement of IC50 values for recombinant scFv anti-idiotypic antibodies against the cell growth of isolates of the Candida species using a CFU assay is described in Materials and Methods.