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Recombinant IL-12 production after M002 and vvD54-M002 infection. IL-12 production after infection with viruses was determined using an ELISA kit (R&D Systems) specific for murine IL-12 p70 heterodimer. Shown are the levels of IL-12 detected after vvD54-M002 or M002 infection of (A) D54-MG cells (72 hpi, P = 0.0124; 84 hpi, P = 0.0093) and (B) Neuro-2a cells (48 hpi, P = 0.0152; 72 hpi, P = 0.0008).
