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Survival of mice bearing human D54-MG brain tumors after vvD54-M002 treatment. Immunocompromised SCID mice bearing D54-MG brain tumors were treated with either saline (closed circles) as a control or 1 × 107 PFU of either R3659 (closed diamonds), M002 (closed squares), or vvD54-M002 (open squares) after 7 days. The survival graph shows two separate studies combined. Cohorts were compared using Kaplan-Meier statistical analysis.
