FIG. 3.

vRAP-modulated recognition patterns reflect epitope presentation. (A) vRAP-modulated recognition patterns of IE1 epitope-specific, L^d-restricted CTLs in ELISPOT assays performed with BALB/c-derived MEFs as stimulator cells expressing all three H-2^d haplotype MHC class I molecules K^d, D^d, and L^d (top panel) or with BALB/c-H-2^dm2-derived MEFs as stimulator cells expressing only K^d and D^d (bottom panel). (B) vRAP-modulated recognition pattern of m04 epitope-specific, D^d-restricted CTLs in an ELISPOT assay performed with BALB/c-derived MEFs as stimulator cells. For ELISPOT assay details, see the legend to Fig. 2. Ø, no vRAP expressed after infection with mCMV-Δm04+06+152; n.i., no infection.