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. 2006 May 5;91(3):793–804. doi: 10.1529/biophysj.106.080945

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Effects of ERP heterogeneity on vulnerability. (A) ERP versus β. β is a parameter that measures the change in Na⁺ conductance and recovery, which is defined as in B. (B) w versus the ERP difference Δr for S2 applied at l = 0. The ERP gradient was generated by linearly changing to mS/cm², and to in a region h = 10 mm, in the same manner as Eq. 2. Uniform mS/cm² was used. Since Na⁺ kinetics has a small effect on APD but a big effect on ERP (as shown in A), the APD distribution in the cable is almost uniform but large ERP gradient occurs.

Inline graphic — Effects of ERP heterogeneity on vulnerability. (A) ERP versus β. β is a parameter that measures the change in Na⁺ conductance and recovery, which is defined as in B. (B) w versus the ERP difference Δr for S2 applied at l = 0. The ERP gradient was generated by linearly changing to mS/cm², and to in a region h = 10 mm, in the same manner as Eq. 2. Uniform mS/cm² was used. Since Na⁺ kinetics has a small effect on APD but a big effect on ERP (as shown in A), the APD distribution in the cable is almost uniform but large ERP gradient occurs.