FIG. 2.

p53^−/− cells accumulate DNA more slowly than do wt cells. p53^−/−, HFF, and THF cells were infected, and cells were harvested for total cellular DNA at the times indicated. Equivalent concentrations of total DNA were slotted in each well. Experiments were performed six (HFF) or three (THF) times. Representative slot blots demonstrating the differences between HFF (top) or THF (bottom) and p53^−/− cell types for viral DNA accumulation over the course of infection are shown.