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. 2006 Sep;80(18):9073–9081. doi: 10.1128/JVI.00515-06

FIG. 1.

FIG. 1.

A. Multiple alignment of 20 partial sequences of hantaviral N proteins. Symbols used in the Clustal program: *, positions that have a single fully conserved residue; :, “strong” groups that are fully conserved; ., “weaker” groups that are fully conserved. Hydrophobic residues comprising a heptad repeat have been shaded. GenBank accession numbers of hantaviral species used in the alignment are the following: Tula virus (TULV), Z69991; Topografov virus (TOPV), AJ01164; Khabarovsk virus (KHAV), U35255; Puumala virus (PUUV), X61035; Prospect Hill virus (PHV), Z49098; Blood Land Lake virus (BLLV), U19303; Isla Vista virus (ISLAV), U19302; Sin Nombre virus (SNV), L25784; New York virus (NYV), U47135; Laguna Negra virus (LANV), AF005727; Rio Mamore virus (RIOMV), U52136; Andes virus (ANDV), U52136; Bayou virus (BAYV), L36929; Black Creek Canal virus (BCCV), L39949; El Moro Canyon hantavirus (ELMCV), U11427; Rio Segundo hantavirus (RIOSV), U18100; Hantaan virus (HTNV), M14626; Seoul virus (SEOV), AF288653; Dobrava virus (DOBV), L41916 and Saaremaa virus (SAAV), AJ009773. B. Prediction of N-protein coiled-coil domains for TULV sequence with various algorithms. (The prediction was also performed for the following virus sequences, marked in boldface: PUUV, SNV, ANDV, HTNV, and SEOV). The two top lines show a prediction of coiled-coils and disordered regions. In the lower lines, “H” corresponds to helix and “E” to beta sheets.