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Viabilities of mutants defective in Vp1-Vp3 interactiona
| NO-SV40 | Viability |
|---|---|
| Wild type | 1.2 × 108 |
| Vp3 F157E-I158E | 1.7 × 105 |
| Vp3 P164R-G165E-G166R | 3.2 × 105 |
| Vp3 P164E-G165R-G166E | 1.8 × 105 |
| Vp3 ΔC13 | 2.0 × 107 |
| Vp1 V243E | <1 |
| Vp1 L245E | 46 |
| Vp1 V243E- L245E | <1 |
Viability was determined as described previously (25) and is based on the number of plaques formed by infection with viral lysate containing 1 μg of replicated viral DNA.
