FIG. 1.

Viral load in LCMV-cgPi mice. (A) Virus titers in brain (white), liver (gray), and blood (black) of LCMV-cgPi mice determined by plaque assay. (B) Levels of viral RNA in brain tissue. RNA was isolated from brain tissue of LCMV-cgPi and mock-infected control mice (6 months old). RNA (equal amounts of each sample) was analyzed by Northern blot hybridization using a DNA probe to LCMV nucleoprotein (NP) that recognizes the S genome RNA (replication) and the NP mRNA (transcription). Samples from three independent mice are shown.