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. 2006 Sep;80(18):9082–9092. doi: 10.1128/JVI.00795-06

TABLE 3.

Known host genes whose expression is changed the brain of LCMV-cgPi micea

GenBank accession no. Value for indicated gene
Gene identity
LCMV-cgPi2/ control 1
LCMV-cgPi2/ control 2
LCMV-cgPi3/ control 1
LCMV-cgPi3/ control 2
Signal ratio P Signal ratio P Signal ratio P Signal ratio P
U43084 2.2 0.000189 1.5 0.000023 2.6 0.000068 2 0.00002 GARG-16
AB067535 2 0.000307 0.9 0.000966 1.4 0.000774 0.3 0.001336 2′-5′ OAS 2
AW047653 1.7 0.00002 1.9 0.00002 1.7 0.00002 1.8 0.00002 UBP43
BQ033138 1.7 0.00003 1.7 0.000023 1.4 0.000114 1.8 0.000078 2′-5′ OAS-like 2
M74124 1.6 0.00006 2 0.00002 1.2 0.000241 1.6 0.000027 Interferon-activated gene 205
M29881 1.5 0.000147 1.6 0.000147 2 0.00006 2 0.000027 MHCI Q region locus 7
BG068242 1.4 0.000052 1.4 0.00003 1.2 0.000346 1.4 0.000346 Tripartite motif protein 30-like
BB757349 1.2 0.00002 1.4 0.00002 1.2 0.00002 1 0.00002 Zinc finger CCCH type, antiviral 1
X67809 1.2 0.000046 1.1 0.000035 1.1 0.000078 1 0.000023 Peptidylprolyl isomerase C-associated
U43086 1.1 0.000046 1.3 0.00002 1.4 0.000052 1.5 0.00002 GARG-49
U51992 0.9 0.000273 1.1 0.000052 0.8 0.000027 1.2 0.00002 IRF9
NM_008326 0.8 0.000052 0.6 0.000438 1.2 0.000035 0.8 0.000774 Interferon inducible protein 1
BM227980 0.8 0.000035 0.7 0.000078 0.7 0.00002 0.7 0.000147 Zinc finger CCCH type domain-containing 1
U06924 0.8 0.000214 0.6 0.00002 1 0.000167 0.9 0.00002 STAT1
NM_008330 0.7 0.00006 1.1 0.000346 1.5 0.000618 1.8 0.000692 Olfactory receptor 56
BC011306 0.7 0.000035 0.8 0.00003 0.7 0.000023 0.9 0.00002 MHCI K region
M86502 0.7 0.00002 0.6 0.00002 0.5 0.00002 0.5 0.00002 MHCIb D region locus 1
NM_011579 0.7 0.000088 1 0.000189 0.8 0.00002 1.1 0.000052 T-cell-specific GTPase
BF715219 0.7 0.00002 0.6 0.00002 0.7 0.00002 0.6 0.00002 Beta-2 microglobulin
NM_010398 0.6 0.000023 0.5 0.000023 0.6 0.00002 0.6 0.00002 MHCI T region locus 23
BB418548 0.5 0.000068 0.5 0.00002 0.7 0.00002 0.9 0.00002 Doublecortin
NM_010758 -0.5 0.99998 −0.5 0.99998 −0.5 0.999977 −0.5 0.00002 Myelin-associated glycoprotein
NM_026731 −0.6 0.999932 −0.4 0.999922 −0.7 0.999965 −0.7 0.00004 Protein phosphatase 1 regulatory subunit 14A
U64572 −0.6 0.999977 −0.8 0.99998 −0.6 0.999922 −0.7 0.00002 Myelin oligodendrocyte glycoprotein
M58045 −0.6 0.99998 −0.5 0.99998 −0.5 0.999693 −0.3 0.00002 Cyclic nucleotide phosphodiesterase 1
BB353220 −0.6 0.999899 −0.6 0.99998 −0.5 0.999899 −0.6 0.00003 LIM and senescent cell antigen-like domains 2
NM_010354 −0.7 0.99998 −0.6 0.99998 −0.6 0.99998 −0.5 0.00002 Gelsolin
NM_008614 −0.7 0.99998 −0.7 0.99998 −0.4 0.999611 −0.4 0.00002 Myelin-associated oligodendrocytic basic protein
BQ175510 −0.7 0.99998 −0.5 0.99998 −0.6 0.99998 −0.4 0.00006 G protein-coupled receptor 37
BC024556 −0.8 0.99998 −0.6 0.999977 −0.6 0.999911 −0.3 0.00008 PDZ and LIM domain 2
AW550625 −0.8 0.999727 −0.8 0.999034 −0.6 0.999611 −0.8 0.007 Procollagen, type III, alpha 1
NM_026174 −0.9 0.999977 −0.8 0.99998 −1 0.999922 −0.9 0.00001 Lysosomal apyrase-like 1
NM_011674 −1 0.99998 −0.8 0.99998 −0.6 0.999977 −0.4 0.0003 UDP-glucuronosyltransferase 8
a

Known host genes with altered expression in brains of LCMV-cgPi mice. Gene expression profiling was performed with total RNA isolated from brain hemispheres of LCMV-cgPi mice 1 and 2 (Table 2) and two controls (mock 1 and 2) by use of the Affymetrix murine genome oligonucleotide DNA array 430 2.0. All four permutations of comparisons between the two LCMV-cgPi mice and the two control animals were made. Genes were identified using the Annotation Tool of the Database for Annotation, Visualization, and Integrated Discovery (DAVID). Displayed are the known host genes that showed consistent regulation of >1.4-fold. The signal ratios for each permutation and the P values of changes are indicated.

b

MHCI, major histocompatibility complex class I.